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Hepatitis C virus core protein triggers expansion and activation of CD4+CD25+ regulatory T cells in...

Hepatitis C virus core protein triggers expansion and activation of CD4+CD25+ regulatory T cells in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4716623

Hepatitis C virus core protein triggers expansion and activation of CD4+CD25+ regulatory T cells in chronic hepatitis C patients

About this item

Full title

Hepatitis C virus core protein triggers expansion and activation of CD4+CD25+ regulatory T cells in chronic hepatitis C patients

Publisher

London: Nature Publishing Group UK

Journal title

Cellular & molecular immunology, 2015-11, Vol.12 (6), p.743-749

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

CD4+CD25+FoxP3 + regulatory T ceils (Tregs) are increased in patients with chronic hepatitis C, which may contribute to the sustained suppression of hepatitis C virus (HCV)-specific T-cell responses and viral persistence in HCV-infected individuals. We postulated that HCV core protein (HCVc) directly contributes to the expansion of Tregs in HCV-inf...

Alternative Titles

Full title

Hepatitis C virus core protein triggers expansion and activation of CD4+CD25+ regulatory T cells in chronic hepatitis C patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4716623

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4716623

Other Identifiers

ISSN

1672-7681

E-ISSN

2042-0226

DOI

10.1038/cmi.2014.119

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