Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and...
Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system
About this item
Full title
Author / Creator
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Summary
Inhibition of the mechanistic target of rapamycin (mTOR) signaling pathway by the FDA‐approved drug rapamycin has been shown to promote lifespan and delay age‐related diseases in model organisms including mice. Unfortunately, rapamycin has potentially serious side effects in humans, including glucose intolerance and immunosuppression, wh...
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Full title
Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4717280
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4717280
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.12405
