Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and i...
Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors
About this item
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Author / Creator
Gao, W , McGarry, T , Orr, C , McCormick, J , Veale, D J and Fearon, U
Publisher
England: Elsevier Limited
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Limited
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Scope and Contents
Contents
BackgroundPsoriatic arthritis (PsA) is a chronic inflammatory disease, characterised by synovitis and destruction of articular cartilage/bone. Janus-kinase and signal transducer and activator of transcription (JAK-STAT) signalling pathway is implicated in the pathogenesis of PsA.ObjectivesTo examine the effect of tofacitinib (JAK inhibitor) on proi...
Alternative Titles
Full title
Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4717390
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4717390
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2014-207201
