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Transcriptome profiling unveils the role of cholesterol in IL-17A signaling in psoriasis

Transcriptome profiling unveils the role of cholesterol in IL-17A signaling in psoriasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4726068

Transcriptome profiling unveils the role of cholesterol in IL-17A signaling in psoriasis

About this item

Full title

Transcriptome profiling unveils the role of cholesterol in IL-17A signaling in psoriasis

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-01, Vol.6 (1), p.19295-19295, Article 19295

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Psoriasis is a chronic inflammatory skin disease characterized by altered proliferation and differentiation of keratinocytes as well as infiltration of immune cells. Increased expression of Th17 cells and cytokines secreted by them provides evidence for its central role in the pathogenesis of psoriasis. IL-17A, signature cytokine of Th17 cells was...

Alternative Titles

Full title

Transcriptome profiling unveils the role of cholesterol in IL-17A signaling in psoriasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4726068

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4726068

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep19295

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