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IFNα enhances the production of IL-6 by human neutrophils activated via TLR8

IFNα enhances the production of IL-6 by human neutrophils activated via TLR8

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4726390

IFNα enhances the production of IL-6 by human neutrophils activated via TLR8

About this item

Full title

IFNα enhances the production of IL-6 by human neutrophils activated via TLR8

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-01, Vol.6 (1), p.19674-19674, Article 19674

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Recently, we reported that human neutrophils produce biologically active amounts of IL-6 when incubated with agonists activating TLR8, a receptor recognizing viral single strand RNA. In this study, we demonstrate that IFNα, a cytokine that modulates the early innate immune responses toward viral and bacterial infections, potently enhances the produ...

Alternative Titles

Full title

IFNα enhances the production of IL-6 by human neutrophils activated via TLR8

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4726390

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4726390

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep19674

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