Null mutation of chloride channel 7 (Clcn7) impairs dental root formation but does not affect enamel...
Null mutation of chloride channel 7 (Clcn7) impairs dental root formation but does not affect enamel mineralization
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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More information
Scope and Contents
Contents
ClC-7, located in late endosomes and lysosomes, is critical for the function of osteoclasts. Secretion of Cl⁻ by the ruffled border of osteoclasts enables H⁺ secretion by v-H⁺-ATPases to dissolve bone mineral. Mice lacking ClC-7 show altered lysosomal function that leads to severe lysosomal storage. Maturation ameloblasts are epithelial cells with...
Alternative Titles
Full title
Null mutation of chloride channel 7 (Clcn7) impairs dental root formation but does not affect enamel mineralization
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4735262
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4735262
Other Identifiers
ISSN
0302-766X
E-ISSN
1432-0878
DOI
10.1007/s00441-015-2263-z
