The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenet...
The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Dual specificity phosphatases are a class of tumor-associated proteins involved in the negative regulation of the MAP kinase pathway. Downregulation of the dual specificity phosphatase 2 (DUSP2) has been reported in cancer. Epigenetic silencing of tumor suppressor genes by abnormal promoter methylation is a frequent mechanism in oncogenesis. It has...
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Full title
The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4736155
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4736155
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-016-2087-6
