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Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice

Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4742374

Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice

Publication information

Publisher

New York: Nature Publishing Group US

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Reducing levels of mitochondrial iron by diet or pharmacological chelation ameliorates symptoms of cigarette smoke–induced chronic obstructive pulmonary disease in mice.
Chronic obstructive pulmonary disease (COPD) is linked to both cigarette smoking and genetic determinants. We have previously identified iron-responsive element–binding protein...

Alternative Titles

Full title

Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4742374

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4742374

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.4021

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