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A pathogenic IFNα, BLyS and IL-17 axis in Systemic Lupus Erythematosus patients

A pathogenic IFNα, BLyS and IL-17 axis in Systemic Lupus Erythematosus patients

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4742957

A pathogenic IFNα, BLyS and IL-17 axis in Systemic Lupus Erythematosus patients

About this item

Full title

A pathogenic IFNα, BLyS and IL-17 axis in Systemic Lupus Erythematosus patients

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-02, Vol.6 (1), p.20651-20651, Article 20651

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

This study aims to analyze in depth the role of IFNα in the upregulation of BLyS in different leukocyte populations and the possible relationship of these molecules with IL-17 and other pathogenic cytokines in SLE. Thus, IFNAR1 and membrane BLyS (mBLyS) expression was upregulated on various blood cell types from patients and closely correlated in a...

Alternative Titles

Full title

A pathogenic IFNα, BLyS and IL-17 axis in Systemic Lupus Erythematosus patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4742957

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4742957

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep20651

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