Distinct genomic and epigenomic features demarcate hypomethylated blocks in colon cancer
Distinct genomic and epigenomic features demarcate hypomethylated blocks in colon cancer
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Large mega base-pair genomic regions show robust alterations in DNA methylation levels in multiple cancers. A vast majority of these regions are hypomethylated in cancers. These regions are generally enriched for CpG islands, Lamin Associated Domains and Large organized chromatin lysine modification domains, and are associated with stochastic varia...
Alternative Titles
Full title
Distinct genomic and epigenomic features demarcate hypomethylated blocks in colon cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4750190
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4750190
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-016-2128-1
