NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis
NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis
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Author / Creator
South, Andrew P. , Purdie, Karin J. , Watt, Stephen A. , Haldenby, Sam , den Breems, Nicoline Y. , Dimon, Michelle , Arron, Sarah T. , Kluk, Michael J. , Aster, Jon C. , McHugh, Angela , Xue, Dylan J. , Dayal, Jasbani H.S. , Robinson, Kim S. , Hasan Rizvi, S.M. , Proby, Charlotte M. , Harwood, Catherine A. and Leigh, Irene M.
Publisher
United States: Elsevier Inc
Journal title
Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Cutaneous SCC (cSCC) is the most frequently occuring skin cancer with metastatic potential and can manifest rapidly as a common side effect in patients receiving systemic kinase inhibitors. Here, we use massively parallel exome and targeted level sequencing of 132 sporadic cSCCs and of 39 squamoproliferative lesions and cSCCs arising in patients re...
Alternative Titles
Full title
NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4753672
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4753672
Other Identifiers
ISSN
0022-202X
E-ISSN
1523-1747
DOI
10.1038/jid.2014.154
