Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica...
Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress
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Author / Creator
Lin, Chen , Zhao, Xinyuan , Sun, Desen , Zhang, Lingda , Fang, Wenpan , Zhu, Tingjia , Wang, Qiang , Liu, Botao , Wei, Saisai , Chen, Guangdi , Xu, Zhengping and Gao, Xiangwei
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Silica nanoparticles (SiO
2
NPs) cause oxidative stress in respiratory system. Meanwhile, human cells launch adaptive responses to overcome SiO
2
NP toxicity. However, besides a few examples, the regulation of SiO
2
NP-responsive proteins and their functions in SiO
2
NP response remain largely unknown. In this study, we demo...
Alternative Titles
Full title
Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4754796
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4754796
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep21133