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Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian...

Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4754861

Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer

About this item

Full title

Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer

Publisher

England: BioMed Central Ltd

Journal title

BMC cancer, 2016-02, Vol.16 (103), p.102-102, Article 102

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

An increasing body of evidence shows that miR-34 family has tumor suppressive properties mediating apoptosis, cell cycle arrest and senescence. In ovarian cancer, miR34 family members were found to be under expressed. Particularly miR-34a has been revealed to be a direct transcriptional target of p53 which is frequently mutated in epithelial ovaria...

Alternative Titles

Full title

Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4754861

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4754861

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/s12885-016-2135-2

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