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PVT1 dependence in cancer with MYC copy-number increase

PVT1 dependence in cancer with MYC copy-number increase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4767149

PVT1 dependence in cancer with MYC copy-number increase

About this item

Full title

PVT1 dependence in cancer with MYC copy-number increase

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2014-08, Vol.512 (7512), p.82-86

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pvt1 overexpression in mice contributes to high Myc levels due to 8q24.21 gain and to MYC-driven tumorigenesis.
An RNA tied to MYC-driven cancers
Many cancer cells carry extra copies of chromosomal region 8q24.21, encompassing the
MYC
oncogene. Anindya Bagchi and colleagues have now investigated the role of a nearby long non-coding RNA...

Alternative Titles

Full title

PVT1 dependence in cancer with MYC copy-number increase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4767149

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4767149

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature13311

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