PVT1 dependence in cancer with MYC copy-number increase
PVT1 dependence in cancer with MYC copy-number increase
About this item
Full title
Author / Creator
Tseng, Yuen-Yi , Moriarity, Branden S. , Gong, Wuming , Akiyama, Ryutaro , Tiwari, Ashutosh , Kawakami, Hiroko , Ronning, Peter , Reuland, Brian , Guenther, Kacey , Beadnell, Thomas C. , Essig, Jaclyn , Otto, George M. , O’Sullivan, M. Gerard , Largaespada, David A. , Schwertfeger, Kathryn L. , Marahrens, York , Kawakami, Yasuhiko and Bagchi, Anindya
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Pvt1 overexpression in mice contributes to high Myc levels due to 8q24.21 gain and to MYC-driven tumorigenesis.
An RNA tied to MYC-driven cancers
Many cancer cells carry extra copies of chromosomal region 8q24.21, encompassing the
MYC
oncogene. Anindya Bagchi and colleagues have now investigated the role of a nearby long non-coding RNA...
Alternative Titles
Full title
PVT1 dependence in cancer with MYC copy-number increase
Authors, Artists and Contributors
Author / Creator
Moriarity, Branden S.
Gong, Wuming
Akiyama, Ryutaro
Tiwari, Ashutosh
Kawakami, Hiroko
Ronning, Peter
Reuland, Brian
Guenther, Kacey
Beadnell, Thomas C.
Essig, Jaclyn
Otto, George M.
O’Sullivan, M. Gerard
Largaespada, David A.
Schwertfeger, Kathryn L.
Marahrens, York
Kawakami, Yasuhiko
Bagchi, Anindya
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4767149
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4767149
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13311