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Hydrogels with tunable stress relaxation regulate stem cell fate and activity

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4767627

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

About this item

Full title

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

Publisher

London: Nature Publishing Group UK

Journal title

Nature materials, 2016-03, Vol.15 (3), p.326-334

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Natural extracellular matrices (ECMs) are viscoelastic and exhibit stress relaxation. However, hydrogels used as synthetic ECMs for three-dimensional (3D) culture are typically elastic. Here, we report a materials approach to tune the rate of stress relaxation of hydrogels for 3D culture, independently of the hydrogel’s initial elastic modulus, deg...

Alternative Titles

Full title

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4767627

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4767627

Other Identifiers

ISSN

1476-1122

E-ISSN

1476-4660

DOI

10.1038/nmat4489

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