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Albumin-bound nanoparticle (nab) paclitaxel exhibits enhanced paclitaxel tissue distribution and tum...

Albumin-bound nanoparticle (nab) paclitaxel exhibits enhanced paclitaxel tissue distribution and tum...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4768222

Albumin-bound nanoparticle (nab) paclitaxel exhibits enhanced paclitaxel tissue distribution and tumor penetration

About this item

Full title

Albumin-bound nanoparticle (nab) paclitaxel exhibits enhanced paclitaxel tissue distribution and tumor penetration

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer chemotherapy and pharmacology, 2015-10, Vol.76 (4), p.699-712

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Purpose
nab
-paclitaxel demonstrates improved clinical efficacy compared with conventional Cremophor EL (CrEL)-paclitaxel in multiple tumor types. This study explored the distinctions in drug distribution between
nab
-paclitaxel and CrEL-paclitaxel and the underlying mechanisms.
Methods
Uptake and transcytosis of paclitaxel were a...

Alternative Titles

Full title

Albumin-bound nanoparticle (nab) paclitaxel exhibits enhanced paclitaxel tissue distribution and tumor penetration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4768222

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4768222

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-015-2833-5

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