Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural pr...
Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
HIV-1 Nef interacts with several cellular proteins, among which the human peroxisomal thioesterase 8 (ACOT8). This interaction may be involved in the endocytosis regulation of membrane proteins and might modulate lipid composition in membrane rafts. Nef regions involved in the interaction have been experimentally characterized, whereas structural d...
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Molecular characterization of HIV-1 Nef and ACOT8 interaction: insights from in silico structural predictions and in vitro functional assays
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4772117
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4772117
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep22319
