N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzym...
N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Neprilysin (NEP) and endothelin converting enzyme-1 (ECE-1) are two enzymes that degrade amyloid beta in the brain. Currently there are no molecules to stimulate the activity of these enzymes. Here we report, the discovery and characterisation of a peptide referred to as K49-P1-20, from the venom of
Bothrops asper
which directly enhances the<...
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Full title
N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4773759
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4773759
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep22413
