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Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally locate...

Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally locate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4773884

Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally located tumours

About this item

Full title

Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally located tumours

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-03, Vol.6 (1), p.22509-22509, Article 22509

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The lack of appropriate mouse models is likely one of the reasons of a limited translational success rate of therapeutic vaccines against cervical cancer, as rapidly growing ectopic tumours are commonly used for preclinical studies. In this work, we demonstrate that the tumour microenvironment of TC-1 tumours differs significantly depending on the...

Alternative Titles

Full title

Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally located tumours

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4773884

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4773884

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep22509

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