Increasing TRPV4 expression restores flow-induced dilation impaired in mesenteric arteries with agin...
Increasing TRPV4 expression restores flow-induced dilation impaired in mesenteric arteries with aging
About this item
Full title
Author / Creator
Du, Juan , Wang, Xia , Li, Jie , Guo, Jizheng , Liu, Limei , Yan, Dejun , Yang, Yunyun , Li, Zhongwen , Zhu, Jinhang and Shen, Bing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The flow-stimulated intracellular Ca
2+
concentration ([Ca
2+
]
i
) rise in endothelial cells is an important early event leading to flow-induced blood vessel dilation. Transient receptor potential vanilloid subtype 4 (TRPV4), a Ca
2+
-permeable cation channel, facilitates the flow-stimulated [Ca
2+
]
i
rise. To...
Alternative Titles
Full title
Increasing TRPV4 expression restores flow-induced dilation impaired in mesenteric arteries with aging
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4780030
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4780030
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep22780
