CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal ade...
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma
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Author / Creator
Noll, Elisa M , Eisen, Christian , Stenzinger, Albrecht , Espinet, Elisa , Muckenhuber, Alexander , Klein, Corinna , Vogel, Vanessa , Klaus, Bernd , Nadler, Wiebke , Rösli, Christoph , Lutz, Christian , Kulke, Michael , Engelhardt, Jan , Zickgraf, Franziska M , Espinosa, Octavio , Schlesner, Matthias , Jiang, Xiaoqi , Kopp-Schneider, Annette , Neuhaus, Peter , Bahra, Marcus , Sinn, Bruno V , Eils, Roland , Giese, Nathalia A , Hackert, Thilo , Strobel, Oliver , Werner, Jens , Büchler, Markus W , Weichert, Wilko , Trumpp, Andreas and Sprick, Martin R
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Expression of HNF1A and KRT81 stratifies pancreatic ductal adenocarcinoma tumors into different subtypes, and expression of cytochrome P450 3A5 mediates basal and/or drug-induced therapy resistance in each subtype.
Although subtypes of pancreatic ductal adenocarcinoma (PDAC) have been described, this malignancy is clinically still treated as a s...
Alternative Titles
Full title
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma
Authors, Artists and Contributors
Author / Creator
Eisen, Christian
Stenzinger, Albrecht
Espinet, Elisa
Muckenhuber, Alexander
Klein, Corinna
Vogel, Vanessa
Klaus, Bernd
Nadler, Wiebke
Rösli, Christoph
Lutz, Christian
Kulke, Michael
Engelhardt, Jan
Zickgraf, Franziska M
Espinosa, Octavio
Schlesner, Matthias
Jiang, Xiaoqi
Kopp-Schneider, Annette
Neuhaus, Peter
Bahra, Marcus
Sinn, Bruno V
Eils, Roland
Giese, Nathalia A
Hackert, Thilo
Strobel, Oliver
Werner, Jens
Büchler, Markus W
Weichert, Wilko
Trumpp, Andreas
Sprick, Martin R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4780258
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4780258
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.4038
