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Molecular mechanisms regulating NLRP3 inflammasome activation

Molecular mechanisms regulating NLRP3 inflammasome activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4786634

Molecular mechanisms regulating NLRP3 inflammasome activation

About this item

Full title

Molecular mechanisms regulating NLRP3 inflammasome activation

Publisher

London: Nature Publishing Group UK

Journal title

Cellular & molecular immunology, 2016-03, Vol.13 (2), p.148-159

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inflammasomes are multi-protein signaling complexes that trigger the activation of inflammatory caspases and the maturation of interleukin-1β. Among various inflammasome complexes, the NLRP3 inflammasome is best characterized and has been linked with various human autoinflammatory and autoimmune diseases. Thus, the NLRP3 inflammasome may be a promi...

Alternative Titles

Full title

Molecular mechanisms regulating NLRP3 inflammasome activation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4786634

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4786634

Other Identifiers

ISSN

1672-7681

E-ISSN

2042-0226

DOI

10.1038/cmi.2015.95

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