Cas9 Variants Expand the Target Repertoire in Caenorhabditis elegans
Cas9 Variants Expand the Target Repertoire in Caenorhabditis elegans
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Publisher
United States: Genetics Society of America
Journal title
Language
English
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Publisher
United States: Genetics Society of America
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Scope and Contents
Contents
The proliferation of CRISPR/Cas9-based methods in Caenorhabditis elegans has enabled efficient genome editing and precise genomic tethering of Cas9 fusion proteins. Experimental designs using CRISPR/Cas9 are currently limited by the need for a protospacer adjacent motif (PAM) in the target with the sequence NGG. Here we report the characterization...
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Full title
Cas9 Variants Expand the Target Repertoire in Caenorhabditis elegans
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4788222
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4788222
Other Identifiers
ISSN
1943-2631,0016-6731
E-ISSN
1943-2631
DOI
10.1534/genetics.115.185041
