Prevention and cure of rotavirus infection via TLR5/NLRC4–mediated production of IL-22 and IL-18
Prevention and cure of rotavirus infection via TLR5/NLRC4–mediated production of IL-22 and IL-18
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Publisher
Washington: American Association for the Advancement of Science
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Language
English
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Publisher
Washington: American Association for the Advancement of Science
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Contents
Activators of innate immunity may have the potential to combat a broad range of infectious agents. We report that treatment with bacterial flagellin prevented rotavirus (RV) infection in mice and cured chronically RV-infected mice. Protection was independent of adaptive immunity and interferon (IFN, type I and II) and required flagellin receptors T...
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Full title
Prevention and cure of rotavirus infection via TLR5/NLRC4–mediated production of IL-22 and IL-18
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4788408
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4788408
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1256999
