Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel co...
Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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In this study, we sought to determine the cellular source of inducible nitric oxide synthase (iNOS) induced in lymphatic endothelial cells (LECs) in response to tumor necrosis factor (TNF), the effects of iNOS on lymphatic smooth muscle cell (LSMC) function and on the development of arthritis in TNF-transgenic (TNF-Tg) mice, and whether iNOS inhibi...
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Full title
Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4789262
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4789262
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ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-016-0963-8
