LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer
LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Tamoxifen, an estrogen receptor (ER) antagonist, is the mainstay treatment of breast cancer and the development of resistance represents a major obstacle for a cure. Although long non-coding RNAs such as HOTAIR have been implicated in breast tumorigenesis, their roles in chemotherapy resistance remain largely unknown. In this study, we report that<...
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LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4791209
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4791209
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2015.340
