A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein
About this item
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Author / Creator
Massignan, Tania , Cimini, Sara , Stincardini, Claudia , Cerovic, Milica , Vanni, Ilaria , Elezgarai, Saioa R. , Moreno, Jorge , Stravalaci, Matteo , Negro, Alessandro , Sangiovanni, Valeria , Restelli, Elena , Riccardi, Geraldina , Gobbi, Marco , Castilla, Joaquín , Borsello, Tiziana , Nonno, Romolo and Biasini, Emiliano
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Prion diseases are rare neurodegenerative conditions associated with the conformational conversion of the cellular prion protein (PrP
C
) into PrP
Sc
, a self-replicating isoform (prion) that accumulates in the central nervous system of affected individuals. The structure of PrP
Sc
is poorly defined and likely to be heterogeneous,...
Alternative Titles
Full title
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4791597
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4791597
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep23180
