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mTORC1 is involved in the regulation of branched‐chain amino acid catabolism in mouse heart

mTORC1 is involved in the regulation of branched‐chain amino acid catabolism in mouse heart

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4794793

mTORC1 is involved in the regulation of branched‐chain amino acid catabolism in mouse heart

About this item

Full title

mTORC1 is involved in the regulation of branched‐chain amino acid catabolism in mouse heart

Publisher

England: John Wiley and Sons Inc

Journal title

FEBS open bio, 2016-01, Vol.6 (1), p.43-49

Language

English

Formats

Publication information

Publisher

England: John Wiley and Sons Inc

More information

Scope and Contents

Contents

The branched‐chain α‐ketoacid dehydrogenase (BCKDH) complex regulates branched‐chain amino acid (BCAA) catabolism by controlling the second step of this catabolic pathway. In the present study, we examined the in vivo effects of treatment with an mTORC1 inhibitor, rapamycin, on cardiac BCKDH complex activity in mice. Oral administration of leucine...

Alternative Titles

Full title

mTORC1 is involved in the regulation of branched‐chain amino acid catabolism in mouse heart

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4794793

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4794793

Other Identifiers

ISSN

2211-5463

E-ISSN

2211-5463

DOI

10.1002/2211-5463.12007

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