Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses
Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Reston viruses are the only Ebolaviruses that are not pathogenic in humans. We analyzed 196 Ebolavirus genomes and identified specificity determining positions (SDPs) in all nine Ebolavirus proteins that distinguish Reston viruses from the four human pathogenic Ebolaviruses. A subset of these SDPs will explain the differences in human pathogenicity...
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Full title
Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4806318
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4806318
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep23743
