Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell...
Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei
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England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Poly(ADP-ribose) (PAR) metabolism participates in several biological processes such as DNA damage signaling and repair, which is a thoroughly studied function. PAR is synthesized by Poly(ADP-ribose) polymerase (PARP) and hydrolyzed by Poly(ADP-ribose) glycohydrolase (PARG). In contrast to human and other higher eukaryotes, Trypanosoma brucei contai...
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Full title
Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4806436
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4806436
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ISSN
1756-3305
E-ISSN
1756-3305
DOI
10.1186/s13071-016-1461-1
