Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming
Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Crystallographic and functional studies reveal the arch-shaped architecture of the Munc13 MUN domain and show the molecular basis for Munc13's role in synaptic-vesicle priming by mediating syntaxin-1 opening and SNARE-complex assembly.
UNC-13-Munc13s have a central function in synaptic-vesicle priming through their MUN domains. However, it is un...
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Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4809529
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4809529
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.3038
