Impaired ROS Scavenging System in Human Induced Pluripotent Stem Cells Generated from Patients with...
Impaired ROS Scavenging System in Human Induced Pluripotent Stem Cells Generated from Patients with MERRF Syndrome
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Myoclonus epilepsy associated with ragged-red fibers (MERRF) is a mitochondrial disorder characterized by myoclonus epilepsy, generalized seizures, ataxia and myopathy. MERRF syndrome is primarily due to an A to G mutation at mtDNA 8344 that disrupts the mitochondrial gene for tRNA(Lys). However, the detailed mechanism by which this tRNA(Lys) mutat...
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Impaired ROS Scavenging System in Human Induced Pluripotent Stem Cells Generated from Patients with MERRF Syndrome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4812254
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4812254
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep23661
