Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fissi...
Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons
About this item
Full title
Author / Creator
Oettinghaus, B , Schulz, J M , Restelli, L M , Licci, M , Savoia, C , Schmidt, A , Schmitt, K , Grimm, A , Morè, L , Hench, J , Tolnay, M , Eckert, A , D'Adamo, P , Franken, P , Ishihara, N , Mihara, K , Bischofberger, J , Scorrano, L and Frank, S
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Well-balanced mitochondrial fission and fusion processes are essential for nervous system development. Loss of function of the main mitochondrial fission mediator, dynamin-related protein 1 (Drp1), is lethal early during embryonic development or around birth, but the role of mitochondrial fission in adult neurons remains unclear. Here we show that...
Alternative Titles
Full title
Synaptic dysfunction, memory deficits and hippocampal atrophy due to ablation of mitochondrial fission in adult forebrain neurons
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4815974
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4815974
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2015.39
