Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase
Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
DNA strand exchange by serine recombinases has been proposed to occur by a large-scale rotation of halves of the recombinase tetramer. Here we provide the first direct physical evidence for the subunit rotation mechanism for the Hin serine invertase. Single-DNA looping assays using an activated mutant (Hin-H107Y) reveal specific synapses between tw...
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Full title
Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4817059
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4817059
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep23697
