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A randomized placebo‐controlled lovastatin trial for neurobehavioral function in neurofibromatosis I

A randomized placebo‐controlled lovastatin trial for neurobehavioral function in neurofibromatosis I

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4818747

A randomized placebo‐controlled lovastatin trial for neurobehavioral function in neurofibromatosis I

About this item

Full title

A randomized placebo‐controlled lovastatin trial for neurobehavioral function in neurofibromatosis I

Publisher

United States: John Wiley & Sons, Inc

Journal title

Annals of clinical and translational neurology, 2016-04, Vol.3 (4), p.266-279

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Objective
Lovastatin has been shown to reverse learning deficits in a mouse model of Neurofibromatosis Type 1 (NF1), a common monogenic disorder caused by a mutation in the Ras‐MAPK pathway and associated with learning disabilities. We conducted a randomized double‐blind placebo‐controlled trial to assess lovastatin's effects on cognition and be...

Alternative Titles

Full title

A randomized placebo‐controlled lovastatin trial for neurobehavioral function in neurofibromatosis I

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4818747

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4818747

Other Identifiers

ISSN

2328-9503

E-ISSN

2328-9503

DOI

10.1002/acn3.288

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