Specific pattern of maturation and differentiation in the formation of cortical tubers in tuberous s...
Specific pattern of maturation and differentiation in the formation of cortical tubers in tuberous sclerosis omplex (TSC): evidence from layer-specific marker expression
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Author / Creator
Mühlebner, Angelika , Iyer, Anand M , van Scheppingen, Jackelien , Anink, Jasper J , Jansen, Floor E , Veersema, Tim J , Braun, Kees P , Spliet, Wim G M , van Hecke, Wim , Söylemezoğlu, Figen , Feucht, Martha , Krsek, Pavel , Zamecnik, Josef , Bien, Christian G , Polster, Tilman , Coras, Roland , Blümcke, Ingmar and Aronica, Eleonora
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Tuberous sclerosis complex (TSC) is a multisystem disorder that results from mutations in the TSC1 or TSC2 genes, leading to constitutive activation of the mammalian target of rapamycin (mTOR) signaling pathway. Cortical tubers represent typical lesions of the central nervous system (CNS) in TSC. The pattern of cortical layering disruption observed...
Alternative Titles
Full title
Specific pattern of maturation and differentiation in the formation of cortical tubers in tuberous sclerosis omplex (TSC): evidence from layer-specific marker expression
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4818922
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4818922
Other Identifiers
ISSN
1866-1947
E-ISSN
1866-1955
DOI
10.1186/s11689-016-9142-0
