Detrimental effects of adenosine signaling in sickle cell disease
Detrimental effects of adenosine signaling in sickle cell disease
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Author / Creator
Zhang, Yujin , Dai, Yingbo , Wen, Jiaming , Zhang, Weiru , Grenz, Almut , Sun, Hong , Tao, Lijian , Lu, Guangxiu , Alexander, Danny C , Milburn, Michael V , Carter-Dawson, Louvenia , Lewis, Dorothy E , Zhang, Wenzheng , Eltzschig, Holger K , Kellems, Rodney E , Blackburn, Michael R , Juneja, Harinder S and Xia, Yang
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Yujin Zhang
et al
. discovered that the concentration of adenosine in the blood is increased both in a mouse model of sickle cell disease and in humans with this disease. Adenosine seems to have a pathological role in this disease, as it induced sickling of human erythrocytes through a mechanism involving activation of the A
2B
adenosin...
Alternative Titles
Full title
Detrimental effects of adenosine signaling in sickle cell disease
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4838392
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4838392
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2280
