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The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells

The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4843825

The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells

About this item

Full title

The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2014-11, Vol.15 (11), p.1055-1063

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The membrane channel TRPV1 is well studied as a pain receptor, but its function beyond sensory neurons remains unclear. Raz and colleagues demonstrate that TRPV1 is also a non–store-operated calcium channel on CD4
+
T cells with an important function in cell activation.
TRPV1 is a Ca
2+
-permeable channel studied mostly as a pain rec...

Alternative Titles

Full title

The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4843825

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4843825

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3009

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