Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols
Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Here, a method is described by which to generate all possible stereoisomers of certain amino alcohols—a protocol that should see use in drug discovery and development, where it is important to determine the differing effects of stereoisomeric drug candidates.
Synthesis of all amino alcohol stereoisomers
The stereochemical dependence of therap...
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Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4844805
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4844805
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature17191