Accumulation of isolevuglandin-modified protein in normal and fibrotic lung
Accumulation of isolevuglandin-modified protein in normal and fibrotic lung
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Author / Creator
Mont, Stacey , Davies, Sean S. , Roberts, L. Jackson , Mernaugh, Raymond L. , McDonald, W. Hayes , Segal, Brahm H. , Zackert, William , Kropski, Jonathan A. , Blackwell, Timothy S. , Sekhar, Konjeti R. , Galligan, James J. , Massion, Pierre P. , Marnett, Lawrence J. , Travis, Elizabeth L. and Freeman, Michael L.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Protein lysine modification by γ-ketoaldehyde isomers derived from arachidonic acid, termed isolevuglandins (IsoLGs), is emerging as a mechanistic link between pathogenic reactive oxygen species and disease progression. However, the questions of whether covalent modification of proteins by IsoLGs are subject to genetic regulation and the identity o...
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Full title
Accumulation of isolevuglandin-modified protein in normal and fibrotic lung
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4847119
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4847119
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep24919
