Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer
Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer
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Author / Creator
Das, T P , Suman, S , Alatassi, H , Ankem, M K and Damodaran, C
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Growth factor-induced activation of protein kinase-B (PKB), also known as AKT, induces pro-survival signaling and inhibits activation of pro-apoptotic signaling molecules including the Forkhead box O-3a (FOXO3a) transcription factor and caspase in transformed prostate cells
in vitro
. Earlier we reported that Withaferin-A (WA), a small herbal...
Alternative Titles
Full title
Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4849149
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4849149
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/cddis.2015.403
