Application of rapid in vitro co-culture system of macrophages and T-cell subsets to assess the immu...
Application of rapid in vitro co-culture system of macrophages and T-cell subsets to assess the immunogenicity of dogs vaccinated with live attenuated Leishmania donovani centrin deleted parasites (LdCen−/−)
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Author / Creator
Viana, Kelvinson Fernandes , Fiuza, Jacqueline Araújo , Gannavaram, Sreenivas , Dey, Ranadhir , Selvapandiyan, Angamuthu , Bartholomeu, Daniella Castanheira , Silveira-Lemos, Denise da , Bueno, Lilian Lacerda , Dutra, Walderez Ornelas , Fujiwara, Ricardo Toshio , Nakhasi, Hira L. and Giunchetti, Rodolfo Cordeiro
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Live attenuated Leishmania donovani parasites as LdCen(-/-) were shown to confer protective immunity against Leishmania infection in mice, hamsters, and dogs. Strong immunogenicity in dogs vaccinated with LdCen(-/-) has been previously reported, including increased antibody response favoring Th1 response lymphoproliferative responses, CD4(+) and CD...
Alternative Titles
Full title
Application of rapid in vitro co-culture system of macrophages and T-cell subsets to assess the immunogenicity of dogs vaccinated with live attenuated Leishmania donovani centrin deleted parasites (LdCen−/−)
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4852444
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4852444
Other Identifiers
ISSN
1756-3305
E-ISSN
1756-3305
DOI
10.1186/s13071-016-1528-z
