In vitro system using human neurons demonstrates that varicella-zoster vaccine virus is impaired for...
In vitro system using human neurons demonstrates that varicella-zoster vaccine virus is impaired for reactivation, but not latency
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Varicella-zoster virus (VZV) establishes latency in human sensory and cranial nerve ganglia during primary infection (varicella), and the virus can reactivate and cause zoster after primary infection. The mechanism of how the virus establishes and maintains latency and how it reactivates is poorly understood, largely due to the lack of robust model...
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Full title
In vitro system using human neurons demonstrates that varicella-zoster vaccine virus is impaired for reactivation, but not latency
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4855584
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4855584
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1522575113
