A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection
A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection
About this item
Full title
Author / Creator
Publisher
Washington: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
Washington: American Association for the Advancement of Science
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Scope and Contents
Contents
Immune cells, including natural killer (NK) cells, recognize transformed cells and eliminate them in a process termed immunosurveillance. It is thought that tumor cells evade immunosurveillance by shedding membrane ligands that bind to the NKG2D-activating receptor on NK cells and/or T cells, and desensitize these cells. In contrast, we show that i...
Alternative Titles
Full title
A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4856222
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4856222
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1258867
