Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TL...
Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation
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Author / Creator
Wu, Yanwei , He, Shijun , Bai, Bingxin , Zhang, Luyao , Xue, Lu , Lin, Zemin , Yang, Xiaoqian , Zhu, Fenghua , He, Peilan , Tang, Wei and Zuo, Jianping
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
We previously reported that SM934, a water-soluble artemisinin derivative, was a viable treatment in murine lupus models. In the current study, we further investigated the therapeutic effects of a modified dosage regimen of SM934 on lupus-prone MRL/
lpr
mice and explored its effects on B cell responses, a central pathogenic event in systemic...
Alternative Titles
Full title
Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4856803
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4856803
Other Identifiers
ISSN
1672-7681
E-ISSN
2042-0226
DOI
10.1038/cmi.2015.13
