Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera tox...
Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
The mucosal adjuvant activity of cholera toxin depends on the microbiota, which signals through Nod2 on CD11c
+
cells.
Cholera toxin (CT) is a potent adjuvant for inducing mucosal immune responses. However, the mechanism by which CT induces adjuvant activity remains unclear. Here we show that the microbiota is critical for inducing antigen...
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Full title
Nod2-mediated recognition of the microbiota is critical for mucosal adjuvant activity of cholera toxin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4860092
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4860092
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.4075
