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p53-dependent SIRT6 expression protects Aβ42-induced DNA damage

p53-dependent SIRT6 expression protects Aβ42-induced DNA damage

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4860716

p53-dependent SIRT6 expression protects Aβ42-induced DNA damage

About this item

Full title

p53-dependent SIRT6 expression protects Aβ42-induced DNA damage

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2016-05, Vol.6 (1), p.25628-25628, Article 25628

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Alzheimer’s disease (AD) is the most common type of dementia and age-related neurodegenerative disease. Elucidating the cellular changes that occur during ageing is an important step towards understanding the pathogenesis and progression of neurodegenerative disorders.
SIRT6
is a member of the mammalian sirtuin family of anti-aging genes. How...

Alternative Titles

Full title

p53-dependent SIRT6 expression protects Aβ42-induced DNA damage

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4860716

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4860716

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep25628

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