A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface
A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
HLA-G, a nonclassical HLA molecule uniquely expressed in the placenta, is a central component of fetus-induced immune tolerance during pregnancy. The tissue-specific expression of HLA-G, however, remains poorly understood. Here, systematic interrogation of the HLA-G locus using massively parallel reporter assay (MPRA) uncovered a previously unident...
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Full title
A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4868469
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4868469
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1602886113