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A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface

A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4868469

A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface

About this item

Full title

A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (19), p.5364-5369

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

HLA-G, a nonclassical HLA molecule uniquely expressed in the placenta, is a central component of fetus-induced immune tolerance during pregnancy. The tissue-specific expression of HLA-G, however, remains poorly understood. Here, systematic interrogation of the HLA-G locus using massively parallel reporter assay (MPRA) uncovered a previously unident...

Alternative Titles

Full title

A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4868469

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4868469

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1602886113

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