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Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and...

Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4871781

Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and FISH

About this item

Full title

Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and FISH

Publisher

Tokyo: Springer Japan

Journal title

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2016-10, Vol.19 (4), p.1066-1079

Language

English

Formats

Publication information

Publisher

Tokyo: Springer Japan

More information

Scope and Contents

Contents

Background
Trastuzumab has shown a survival benefit in cases of Her2-positive gastroesophageal cancer (GEC). Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) currently determine eligibility for trastuzumab-based therapy. However, these low-throughput assays often produce discordant or equivocal results.
Methods
We d...

Alternative Titles

Full title

Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and FISH

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4871781

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4871781

Other Identifiers

ISSN

1436-3291

E-ISSN

1436-3305

DOI

10.1007/s10120-015-0566-0

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