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Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis

Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4872667

Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis

About this item

Full title

Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory and critical care medicine, 2016-05, Vol.193 (10), p.1111-1122

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

Hemolysis occurs not only in conditions such as sickle cell disease and malaria but also during transfusion of stored blood, extracorporeal circulation, and sepsis. Cell-free Hb depletes nitric oxide (NO) in the vasculature, causing vasoconstriction and eventually cardiovascular complications. We hypothesize that Hb-binding proteins may preserve va...

Alternative Titles

Full title

Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4872667

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4872667

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.201510-2058OC

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