Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis
Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis
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Publisher
United States: American Thoracic Society
Journal title
Language
English
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Publisher
United States: American Thoracic Society
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Scope and Contents
Contents
Hemolysis occurs not only in conditions such as sickle cell disease and malaria but also during transfusion of stored blood, extracorporeal circulation, and sepsis. Cell-free Hb depletes nitric oxide (NO) in the vasculature, causing vasoconstriction and eventually cardiovascular complications. We hypothesize that Hb-binding proteins may preserve va...
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Full title
Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4872667
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4872667
Other Identifiers
ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.201510-2058OC